AI-native venture group

The signals were always there. Now we build on them.

Define is an AI-native venture group. We build companies, back founders with early concepts, and acquire the ones that fit, then own and grow them for the long term. Each turns the signals hidden in a domain’s data into what to do next.

What we mean by a signal

A signal is the pattern in complex data that was invisible before AI, and decisive once you see it. In a body, it is the reason last night’s sleep should change today’s training. In the mind, in biology, in performance, it is the same idea: an insight that was always there, finally legible, and turned into action. Define exists to find those signals and build the companies that act on them.

Three ways in. One owner.

Define does not spin companies out. What we build, back, or buy, we keep, sharing foundations and compounding over time.

01

Build

Some ventures are conceived and built inside Define, from the first line of code. Malkolm is one.

02

Partner

Founders who have taken an idea to alpha or beta, and see it fitting Define’s thesis, build it out with us: our foundations, backing, and operating model behind them, instead of going it alone.

03

Acquire

Define acquires AI-native companies that belong in the house and gives them a permanent home.

Selected work

One venture live. More in the making.

Malkolm

Your health data finally talks back.

Health · AI Live

Malkolm

Chief of Staff for your Body

He connects your whole health picture (wearables, sleep, workouts, meals, even your lab reports) and turns it into the one thing your apps never give you: what to do today. Your whole health. One clear move.

Your move

Shared foundations, separate identities

Each venture keeps its own name, voice, and momentum. What they share is Define’s foundations: a bias toward trust, a commitment to human benefit, and the conviction that AI puts once-impossible insight within reach. We own for the long term, so we build for it.

Where we look

  • 01Health
  • 02Biotech
  • 03Fitness
  • 04Wellness, in body and mind

Domains where the data is rich, the signals are real, and no one has turned them into action yet.

Malkolm is a chief of staff for your body. The same model reaches the mind, and further.

Work with Define

For founders

Built something early?

If you have taken an AI-native concept to alpha or beta and it fits where Define is headed, let’s talk. You bring the insight and the momentum. We bring the foundations, the backing, and a permanent home for what you build, instead of building it alone.

For investors

Back the group, not a bet.

Define is building a durable group of AI-native companies, owned for the long term so the model and the value compound rather than scatter. One venture is live and proving the playbook; more are on the way, by build, partnership, and acquisition. If you back category-defining AI-native companies, let’s talk.